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Article

Genetic characterization of rbt mutants that enhance basal transcription from core promoters in Saccharomyces cerevisiae.

Journal of biochemistry - 1 Oct 2000

Kunoh T, Sakuno T, Furukawa T, Kaneko Y, Harashima S

Abstract excerpt

While this Saccharomyces cerevisiae SIN4 gene product is a component of a mediator complex associated with RNA polymerase II, various studies suggest the involvement of Sin4 in the alteration of higher-order chromatin structure. Our previous analysis of a sin4 mutant suggested that the mechanisms of transcriptional repression by Sin4 (mediator) and the Tup1-Ssn6 complex (general repressor) are different. To...

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PMID: 11011139
DOI: 10.1093/oxfordjournals.jbchem.a022789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Genetic characterization of rbt mutants that enhance basal transcription from core promoters in Saccharomyces cerevisiae.PMID 11011139Read ↗

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