Article
Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast.
Molecular genetics and genomics : MGG - 1 Apr 2003
Mizuno T, Harashima S
Abstract excerpt
Mutations in SIN4, which encodes a global transcriptional regulator in Saccharomyces cerevisiae, have been suggested to lead to an increase in basal transcription of various genes by causing an alteration in chromatin structure. We reported previously that this activation of basal transcription occurs via a mechanism that differs from activator-mediated transcriptional enhancement. This finding prompted us to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
