Article
Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein.
Human molecular genetics - 22 Sept 2000
Tanahashi H, Tabira T
Abstract excerpt
Using the yeast two-hybrid system, we screened for proteins interacting with presenilin 2 (PS2) and cloned DRAL. DRAL is an LIM-only protein containing four LIM domains and an N-terminal half LIM domain. Previously DRAL has been cloned as a co-activator of the androgen receptor and as a protein interacting with a DNA replication regulatory protein, hCDC47. Our yeast two-hybrid assay showed that DRAL interacted...
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