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Article

A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25.

FEBS letters - 11 Dec 1998

Noto S, Maeda T, Hattori S, Inazawa J, Imamura M, Asaka M, Hatakeyama M

Abstract excerpt

We report the molecular cloning of a human cDNA that encodes a molecule having striking homology with Ras-specific GTPase-activating proteins (RasGAPs). Among previously described RasGAPs, the cDNA product is most closely related to Caenorhabditis elegans GAP-2, including a predicted coiled-coil structure near the carboxyl terminus. Expression of the cDNA in Saccharomyces cerevisiae defective in one of two...

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Identifiers

PMID: 9877179
DOI: 10.1016/s0014-5793(98)01530-0

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