A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25.

doi:10.1016/s0014-5793(98)01530-0

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Article

A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25.

FEBS letters - 11 Dec 1998

Noto S, Maeda T, Hattori S, Inazawa J, Imamura M, Asaka M, Hatakeyama M

Abstract excerpt

We report the molecular cloning of a human cDNA that encodes a molecule having striking homology with Ras-specific GTPase-activating proteins (RasGAPs). Among previously described RasGAPs, the cDNA product is most closely related to Caenorhabditis elegans GAP-2, including a predicted coiled-coil...

Topics

Amino Acid Sequence
Chromosome Mapping
Chromosomes, Human, Pair 1
Consensus Sequence
DNA, Complementary
GTPase-Activating Proteins
Genetic Predisposition to Disease
Humans
Male
Molecular Sequence Data
Prostatic Neoplasms
Proteins
Recombinant Proteins
Sequence Alignment
Sequence Homology, Amino Acid
ras GTPase-Activating Proteins
ras Proteins

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Identifiers

PMID: 9877179
DOI: 10.1016/s0014-5793(98)01530-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9877179-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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