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Article

Interaction of Doppel with the full-length laminin receptor precursor protein.

Archives of biochemistry and biophysics - 15 Aug 2004

Yin Shao-Man, Sy Man-Sun, Yang Huai-Yi, Tien Po

Abstract excerpt

Doppel (Dpl) is a homolog of normal cellular prion protein (PrPc) with unknown functions. Ectopic expression of Dpl in the central nervous system (CNS) causes neurotoxicity and this effect is rescued by the expression of PrPc. However, the molecular basis for the protective effect of PrPc remains unclear. Using a yeast two-hybrid system, we showed that Dpl binds the full-length 37-kDa laminin receptor precursor...

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Source

Identifiers

PMID: 15246873
DOI: 10.1016/j.abb.2004.06.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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