Article
Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway.
Molecular and cellular biology - 1 Oct 1997
Sugimoto K, Ando S, Shimomura T, Matsumoto K
Abstract excerpt
The RFC5 gene encodes a small subunit of replication factor C (RFC) complex in Saccharomyces cerevisiae. We have previously shown that a temperature-sensitive (ts) rfc5-1 mutation is impaired in the S-phase checkpoint. In this report, we show that the rfc5-1 mutation is sensitive to DNA-damaging...
Topics
- Cell Cycle Proteins
- Checkpoint Kinase 2
- DNA Damage
- DNA Replication
- DNA-Binding Proteins
- Fungal Proteins
- G2 Phase
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Homeodomain Proteins
- Hydroxyurea
- Methyl Methanesulfonate
- Minor Histocompatibility Antigens
- Mutagens
- Mutation
- Phosphorylation
- Phosphotransferases (Alcohol Group Acceptor)
- Protein Kinases