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Article

Inactivation of myosin heavy chain genes in the mouse: diverse and unexpected phenotypes.

Microscopy research and technique - 15 Sept 2000

Allen D L, Harrison B C, Leinwand L A

Abstract excerpt

Myosin heavy chain (MyHC) is a critical component of the cellular contractile apparatus. The mammalian genome contains two nonmuscle, two smooth muscle, and eight striated muscle isoforms of MyHC. Within each class of genes, there is extremely high sequence homology among different MyHC isoforms, raising the question of whether these isoforms are functionally redundant or whether they perform unique roles in cell...

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Identifiers

PMID: 10998638
DOI: 10.1002/1097-0029(20000915)50:6<492::AID-JEMT6>3.0.CO;2-J

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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