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Article

The role of vertebrate nonmuscle Myosin II in development and human disease

12 Mar 2014

Abstract excerpt

Three different genes each located on a different chromosome encode the heavy chains of nonmuscle myosin II in humans and mice. This review explores the functional consequences of the presence of three isoforms during embryonic development and beyond. The roles of the various isoforms in cell division, cell-cell adhesion, blood vessel formation and neuronal cell migration are addressed in animal models and at the...

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Identifiers

PMID: 25098841
DOI: 10.4161/bioa.29766

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