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Article

Simultaneous determination of polymorphism in N-acetyltransferase 1 and 2 genes by reverse line blot hybridization.

Analytical biochemistry - 1 Oct 2000

Bunschoten A, Tiemersma E, Schouls L, Kampman E

Abstract excerpt

Polymorphism in N-acetyltransferases NAT1 and NAT2 may contribute to differences in cancer susceptibility of subjects exposed to alkylating compounds. We developed a robust method for simultaneous determination of these NAT polymorphisms: Reverse line blot (RLB) hybridization, based on PCR followed by allele-specific oligo hybridization. On a membrane, allele-specific oligonucleotide probes of the NAT genes...

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Source

Identifiers

PMID: 10998276
DOI: 10.1006/abio.2000.4742

Genes

NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Simultaneous determination of polymorphism in N-acetyltransferase 1 and 2 genes by reverse line blot hybridization.PMID 10998276Read ↗

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