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Article

A pilot study investigating the role of NAT1 and NAT2 polymorphisms in gastric adenocarcinoma.

International journal of cancer - 15 Aug 2000

Boissy R J, Watson M A, Umbach D M, Deakin M, Elder J, Strange R C, Bell D A

Abstract excerpt

In humans, aromatic and heterocyclic amine carcinogens may be acetylated by the expression products of either of the N-acetyltransferase genes, NAT1 or NAT2. This conjugation reaction can result in either activation or detoxication of these carcinogens depending on the tissue involved. Recent studies suggest that polymorphisms in NAT1 or NAT2 may modulate cancer risk. To determine if genetic differences in NAT1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10918189

Genes

NAT1
NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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