Article
Rapid N-acetyltransferase 2 imputed phenotype and smoking may increase risk of colorectal cancer in women (Netherlands).
Cancer causes & control : CCC - 1 Apr 2003
van der Hel Olga L, Bueno de Mesquita H Bas, Sandkuijl Lodewijk, van Noord Paul A H, Pearson Peter L, Grobbee Diederick E, Peeters Petra H M
Abstract excerpt
OBJECTIVE: The relationship between smoking and colorectal cancer risk and whether such effect is modified by variations in the NAT2 genotype is investigated. METHODS: In the prospective DOM (Diagnostisch Onderzoek Mammacarcinoom; 27,722 women) cohort follow-up from 1976 until 1987 revealed 54 deaths due to colon or rectal cancer, and follow-up from 1987 to 01-01-1996 revealed 204 incident colorectal cancer...
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