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Article

Evidence for a role of HLA DRB1 alleles in the control of IgE levels, strengthened by interacting TCR A/D marker alleles.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Oct 2000

Mansur A H, Williams G A, Bishop D T, Markham A F, Lewis S, Britton J, Morrison J F

Abstract excerpt

BACKGROUND: MHC class II alleles at human chromosome 6p21.1 and alleles in the TCR A/D locus at human chromosome 14q11.2 have been implicated in susceptibility to specific allergies and the modulation of total serum IgE. It has also been hypothesized that HLA and TCR allelic interactions may have a strong influence on predisposition to allergic disease. OBJECTIVE: This study was performed to investigate the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10998012
DOI: 10.1046/j.1365-2222.2000.00944.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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