Article
Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample.
European journal of human genetics : EJHG - 1 May 2001
Moffatt M F, Schou C, Faux J A, Abecasis G R, James A, Musk A W, Cookson W O
Abstract excerpt
The region of human chromosome 6 containing the MHC has been identified as influencing asthma and atopy (allergy) by several genome-wide searches. The MHC contains many genes with potential effects on innate and specific immunity. As a first step in dissecting MHC influences on asthma and its underlying quantitative phenotypes, we have examined the HLA-DRB1 locus in a population sample consisting of 1004...
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