Article
Associations between specific IgE sensitization to 26 respiratory allergen molecules and HLA class II alleles in the EGEA cohort.
Allergy - 1 Aug 2021
Gheerbrant Hubert, Guillien Alicia, Vernet Raphaël, Lupinek Christian, Pison Christophe, Pin Isabelle, Demenais Florence, Nadif Rachel, Bousquet Jean, Pickl Winfried F, Valenta Rudolf, Bouzigon Emmanuelle, Siroux Valérie
Abstract excerpt
BACKGROUND: Allergy, the most frequent immune disorder affecting 30% of the world's population, is the consequence of immunoglobin E (IgE) sensitization to allergens. Among the genetic factors suspected to be involved in allergy, the HLA class-II genomic region is a strong candidate. OBJECTIVE: To assess the association between HLA class-II alleles and specific IgE (sIgE) sensitization to a large number of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.