Association and linkage analyses of interleukin-6 gene 634C/G polymorphism and bone phenotypes in Chinese.

doi:10.1007/s00774-004-0607-y

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Article

Association and linkage analyses of interleukin-6 gene 634C/G polymorphism and bone phenotypes in Chinese.

Journal of bone and mineral metabolism - 1 Jan 2005

Lei Shu-Feng, Liu Yao-Zhong, Deng Fei-Yan, Li Yu-Mei, Li Miao-Xin, Deng Hong-Wen

Abstract excerpt

In this study, we tested the interleukin-6 (IL-6) gene as an important candidate gene for its linkage and association with the variation of bone phenotypes (bone mineral density [BMD] and bone size) in young Chinese female subjects. We genotyped the IL-6 gene at the -634C/G restriction fragment length polymorphism (RFLP) site (ID, RS1800796) in 1263 individuals from 402 Chinese nuclear families, composed of both...

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PMID: 15981030
DOI: 10.1007/s00774-004-0607-y

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