Article
Association of radial bone mineral density with CA repeat polymorphism at the interleukin 6 locus in postmenopausal Japanese women.
Journal of human genetics - 1 Jan 1999
Tsukamoto K, Yoshida H, Watanabe S, Suzuki T, Miyao M, Hosoi T, Orimo H, Emi M
Abstract excerpt
Twin studies have shown strong correlations between bone mass and genetic factors. Some of the genes involved could regulate bone metabolism and bone formation and resorption, all processes that determine bone mass. One candidate gene, interleukin 6 (IL-6), has been implicated in the pathogenesis of bone loss because it stimulates osteoclasts. We investigated a possible association between the CA repeat...
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