Article
Interleukin-6 gene polymorphism is related to bone mineral density during and after puberty in healthy white males: a cross-sectional and longitudinal study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2000
Lorentzon M, Lorentzon R, Nordström P
Abstract excerpt
Bone mineral density (BMD) is under strong genetic control and is the major determinant of fracture risk. The cytokine interleukin-6 (IL-6) is an important regulator of bone metabolism and is involved in mediating the effects of androgens and estrogens on bone. Recently, a G/C polymorphism in pos...
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