Article
Polymorphisms of the interleukin-6 gene are associated with bone mineral density.
Bone - 1 Jul 1997
Murray R E, McGuigan F, Grant S F, Reid D M, Ralston S H
Abstract excerpt
Genetic factors play an important role in determining bone mass and several genes probably act as regulators of this process. Interleukin-6 (IL-6) is a candidate gene for regulation of bone density, since it has stimulatory effects on cells of the osteoclast lineage and has been implicated in the pathogenesis of bone loss associated with estrogen deficiency. Here we studied the relationship between bone mineral...
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