Article
Herpes simplex virus types 1 and 2 differ in their interaction with heparan sulfate.
Journal of virology - 1 Oct 2000
Trybala E, Liljeqvist J A, Svennerholm B, Bergström T
Abstract excerpt
Cell surface heparan sulfate (HS) serves as an initial receptor for many different viruses, including herpes simplex virus types 1 and 2 (HSV-1 and 2, respectively). Glycoproteins C and B (gC and gB) are the major components of the viral envelope that mediate binding to HS. In this study, purified gB and gC homologous proteins as well as purified HSV-1 and HSV-2 virions were compared for the ability to bind...
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