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Syndecan-1 and syndecan-2 play key roles in herpes simplex virus type-1 infection

9 Dec 2010

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) is an important human pathogen and a leading cause of infectious blindness in the developed world. HSV-1 exploits heparan sulfate proteoglycans (HSPG) for attachment to cells. While the significance of heparan sulphate (HS) moieties in HSV-1 infection is well established, the role of specific proteoglycan core proteins in the infection process remains poorly understood. The...

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PMID: 21148276
DOI: 10.1099/vir.0.027052-0

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