Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Herpes Simplex Virus Type‐1 (HSV‐1) Entry into Human Mesenchymal Stem Cells Is Heavily Dependent on Heparan Sulfate

1 Jan 2011

Abstract excerpt

Hematopoietic stem cells recipients remain susceptible to opportunistic viral infections including herpes simplex virus type-1 (HSV-1). The purpose of this investigation was to analyze susceptibility of human mesenchymal stem cells (hMSCs) to HSV-1 infection and identify the major entry receptor. Productive virus infection in hMSCs was confirmed by replication and plaque formation assays using a syncytial HSV-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Herpesvirus Infections and Treatments
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21799659
DOI: 10.1155/2011/264350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Herpes Simplex Virus Type‐1 (HSV‐1) Entry into Human Mesenchymal Stem Cells Is Heavily Dependent on Heparan SulfatePMID 21799659Read ↗

Syndecan-1 and syndecan-2 play key roles in herpes simplex virus type-1 infectionSemantic proximity Read ↗

Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entrySemantic proximity Read ↗

Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1Semantic proximity Read ↗

Early Events in Herpes Simplex Virus Lifecycle with Implications for an Infection of LifetimeSemantic proximity Read ↗

Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected CellsSemantic proximity Read ↗

Mutations in the N termini of herpes simplex virus type 1 and 2 gDs alter functional interactions with the entry/fusion receptors HVEM, nectin-2, and 3-O-sulfated heparan sulfate but not with nectin-1.Semantic proximity Read ↗

Heparanase-Regulated Syndecan-1 Shedding Facilitates Herpes Simplex Virus 1 EgressSemantic proximity Read ↗

Pteropine orthoreoviruses use cell surface heparan sulphate as an attachment receptorSemantic proximity Read ↗

The Degree of Polymerization and Sulfation Patterns in Heparan Sulfate are Critical Determinants of Cytomegalovirus Entry into Host CellsSemantic proximity Read ↗

Herpes simplex virus types 1 and 2 differ in their interaction with heparan sulfate.Semantic proximity Read ↗

Herpes simplex virus infects most cell types in vitro: clues to its successSemantic proximity Read ↗

An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.