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Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells

30 Sept 2022

Abstract excerpt

. Establishment of its productive infection and progression of disease pathologies depend largely on successful release of virions from the virus-producing cells. HSV-1 is known to exploit many host factors for its release. Recent studies have shown that heparanase (HPSE) is one such host enzyme that is recruited for this purpose. It is an endoglycosidase that cleaves heparan sulfate (HS) from the surface of...

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PMID: 36298711
DOI: 10.3390/v14102156

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