Article
Open field activity and EtOH activation of gamma-PKC null mutants.
Addiction biology - 1 Dec 2003
Hix D M, Bowers B J, Miyamoto J H, Wehner J M
Abstract excerpt
Null mutants of the neural-specific gamma-isotype of protein kinase C (gamma-PKC) have demonstrated differential responses to acute administration of ethanol in comparison with wild-type animals. Previous studies have shown that the mutants are less sensitive to ethanol-induced loss of righting response. Null mutants also consume more ethanol and exhibit less behavioral inhibition. In order to determine if these...
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