Article
Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22.
Oncogene - 24 Aug 2000
Rahman N, Teare M D, Seal S, Renard H, Mangion J, Cour C, Thompson D, Shugart Y, Eccles D, Devilee P, Meijers H, Nathanson K L, Neuhausen S L, Weber B, Chang-Claude J, Easton D F, Goldgar D, Stratton M R
Abstract excerpt
Several recent studies indicate that the majority of families with five or fewer cases of breast cancer and no cases of ovarian cancer are not due to BRCA1 or BRCA2. It has been proposed that a further breast cancer susceptibility gene that may account for some of these families is located on chromosome 8p12-p22. We have identified 31 site-specific breast cancer families that have a greater than 80% posterior...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.