Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational paths towards increased fluoroquinolone resistance in Legionella pneumophila

27 May 2009

Abstract excerpt

OBJECTIVES: Fluoroquinolone resistance has been poorly studied in Legionella pneumophila, an intracellular pathogen responsible for legionellosis. Our goal was to further characterize molecular mechanisms involved in fluoroquinolone resistance in this species. METHODS: Eight independent lineages were founded from a common fluoroquinolone-susceptible L. pneumophila ancestor and propagated by serial passages in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Legionella and Acanthamoeba research
Share to Pneumonia and Respiratory Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19474069
DOI: 10.1093/jac/dkp173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational paths towards increased fluoroquinolone resistance in Legionella pneumophilaPMID 19474069Read ↗

Development and mechanism of fluoroquinolone resistance in Legionella pneumophila.Semantic proximity Read ↗

Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila.Semantic proximity Read ↗

Hidden Selection of Bacterial Resistance to Fluoroquinolones In Vivo: The Case of Legionella pneumophila and Humans.Semantic proximity Read ↗

Emerging Mechanisms of Fluoroquinolone ResistanceSemantic proximity Read ↗

Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success.Semantic proximity Read ↗

Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication.Semantic proximity Read ↗

Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa.Semantic proximity Read ↗

Global Evolution of Pathogenic Bacteria With Extensive Use of Fluoroquinolone AgentsSemantic proximity Read ↗

In Vitro Derivation of Fluoroquinolone-Resistant Mutants from Multiple Lineages of Haemophilus influenzae and Identification of Mutations Associated with Fluoroquinolone Resistance.Semantic proximity Read ↗

The landscape of intrinsic and evolved fluoroquinolone resistance in <i>Acinetobacter baumannii</i> includes suppression of drug-induced prophage replicationSemantic proximity Read ↗

In vitro dynamics and mechanisms of cefiderocol resistance development in wild-type, mutator and XDR Pseudomonas aeruginosaSemantic proximity Read ↗

Evolution toward high-level fluoroquinolone resistance in Francisella speciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.