Article
Fluoroquinolone resistance in Streptococcus pneumoniae from a university hospital, Thailand.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Nov 2010
Srifuengfung Somporn, Tribuddharat Chanwit, Chokephaibulkit Kulkanya, Comerungsee Sopita
Abstract excerpt
The most frequent markers of fluoroquinolone resistance in S. pneumoniae are chromosomal mutations in the quinolone-resistance-determining regions of DNA gyrase and topoisomerase IV encoding for the gyrA, gyrB and parC, parE genes. In 2008, 6.5% of the Streptococcus pneumoniae isolates in a Bangk...
Topics
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- Anti-Bacterial Agents
- DNA Gyrase
- DNA Topoisomerase IV
- Disk Diffusion Antimicrobial Tests
- Drug Resistance, Microbial
- Female
- Fluoroquinolones
- Hospitals, University
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction