Article
Susceptibility to ozone-induced inflammation. II. Separate loci control responses to acute and subacute exposures.
The American journal of physiology - 1 Jan 1993
Kleeberger S R, Levitt R C, Zhang L Y
Abstract excerpt
We demonstrated previously that inbred strains of mice are differentially susceptible to acute (3 h) and subacute (48 h) exposures to 2 parts per million (ppm) ozone (O3) and 0.30 ppm O3, respectively. Genetic studies with O3-resistant C3H/HeJ and O3-susceptible C57BL/6J strains have indicated that susceptibility to each of these O3 exposures is under Mendelian (single gene) control. In the present study, we...
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