Article
Molecular epidemiology of EBNA-1 substrains of Epstein-Barr virus in posttransplant lymphoproliferative disorders which have infrequent p53 mutations.
Leukemia & lymphoma - 1 Aug 2000
Greiner T C, Abou-Elella A A, Smir B N, Orazi A, Hinrichs S, Anderson J, Gross T, Bierman P, Hauke R
Abstract excerpt
Posttransplant lymphoproliferative disorders (PTLDs), which are highly associated with Epstein-Barr virus infection, have a low frequency of molecular genetic abnormalities. Recently it has been suggested certain EBV substrains may be associated with specific lymphoma subtypes. The goals of our study were two fold: 1) to determine the prevalence of EBNA-1 substrains and prognostic utility in PTLD and 2) to...
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