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Article

Posttransplantation lymphoproliferative disorders frequently contain type A and not type B Epstein-Barr virus

1 Mar 1995

Abstract excerpt

Two families of Epstein-Barr virus (EBV), type A and type B, have been defined on the basis of sequence divergence in the EBNA-2 gene. Type A EBV immortalizes B cells more efficiently in vitro and infects immunocompetent individuals more commonly than type B EBV. However, increased rates of infection by type B EBV are seen in immunocompromised hosts and in many lymphoid neoplasms associated with immunocompromise....

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PMID: 7858270
DOI: 10.1182/blood.v85.5.1396.bloodjournal8551396

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