Article
Molecular epidemiology of deletions and mutations of the latent membrane protein 1 oncogene of the Epstein-Barr virus in posttransplant lymphoproliferative disorders.
Laboratory investigation; a journal of technical methods and pathology - 1 Oct 1996
Smir B N, Hauke R J, Bierman P J, Gross T G, d'Amore F, Anderson J R, Greiner T C
Abstract excerpt
Latent membrane protein 1 (LMP1) is a protooncogene of the Epstein-Barr virus (EBV) that is expressed in most EBV-positive posttransplant lymphoproliferative disorders (PTLD). Small deletions in the carboxy-terminal domain of LMP1 have been recently described in Hodgkin's disease, nasopharyngeal carcinoma, and non-Hodgkin's lymphoma. We characterized the deletions and point mutations of LMP1 in 32 PTLD and 8...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.