Article
Analysis of Epstein-Barr virus (EBV) nuclear antigen 1 subtypes in EBV-associated lymphomas from Brazil and the United Kingdom.
The Journal of general virology - 1 Oct 1999
MacKenzie Jane, Gray Diane, Pinto-Paes Roberto, Barrezueta Luis F M, Armstrong Alison A, Alexander Freda A, McGeoch Duncan J, Jarrett Ruth F
Abstract excerpt
EBNA-1 is the only viral protein consistently expressed in all cells latently infected by Epstein-Barr virus (EBV). There is a high frequency of sequence variation within functionally important domains of EBNA-1, with five subtypes identified. Individuals may be infected with multiple EBV strains (classified according to EBNA-1 subtype), but Burkitt's lymphoma (BL) tumours carry a single subtype and exhibit some...
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