Article
A skeletal muscle-specific mouse Igf2 repressor lies 40 kb downstream of the gene.
Development (Cambridge, England) - 1 Sept 2000
Ainscough J F, John R M, Barton S C, Surani M A
Abstract excerpt
Igf2 and H19 are closely linked and reciprocally expressed genes on distal chromosome 7 in the mouse. We have previously shown that a 130 kb YAC transgene contains multiple tissue-specific enhancers for expression of both genes during embryogenesis. The YAC also contains all the crucial elements responsible for initiating and maintaining appropriate parent-of-origin-specific expression of these genes at ectopic...
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