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Article

Imprinting of Igf2 and H19 from a 130 kb YAC transgene.

Development (Cambridge, England) - 1 Sept 1997

Ainscough J F, Koide T, Tada M, Barton S, Surani M A

Abstract excerpt

A stringent test for imprint control elements is to examine their function at ectopic loci in transgenic experiments. Igf2 and H19 are part of a larger imprinting region and as a first step, we examined these reciprocally imprinted genes in transgenic experiments using a 130 kb YAC clone. After paternal inheritance, H19 was appropriately repressed and Igf2 was expressed, irrespective of copy number or genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9342054
DOI: 10.1242/dev.124.18.3621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Imprinting of Igf2 and H19 from a 130 kb YAC transgene.PMID 9342054Read ↗

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