Article
Multiple Mechanisms Regulate Imprinting of the Mouse Distal Chromosome 7 Gene Cluster
1 Jun 1998
Abstract excerpt
Genomic imprinting is an epigenetic process that results in the preferential silencing of one of the two parental copies of a gene. Although the precise mechanisms by which genomic imprinting occurs are unknown, the tendency of imprinted genes to exist in chromosomal clusters suggests long-range regulation through shared regulatory elements. We characterize a 800-kb region on the distal end of mouse chromosome 7...
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