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Article

A Korean family of familial medullary thyroid cancer with Cys618Ser RET germline mutation.

Journal of Korean medical science - 1 Feb 2010

Jung Jinhyang, Uchino Shinya, Lee Youngha, Park Hoyong

Abstract excerpt

Familial medullary thyroid carcinoma (FMTC) is caused by autosomal dominant gain-of-function mutations in the RET proto-oncogene. An identifiable RET mutation can be detected in about 85% of FMTC families. The majority of germline mutations in FMTC have been found in exons 10 and 11 of the RET proto-oncogene, specifically within the cysteine codons 609, 611, 618, 620, and 634. We screened members of a large...

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Source

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Identifiers

PMID: 20119574
DOI: 10.3346/jkms.2010.25.2.226
PMCID: PMC2811288

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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