Hereditary medullary thyroid carcinoma: the management dilemma.

doi:10.1007/s10689-011-9501-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Hereditary medullary thyroid carcinoma: the management dilemma.

Familial cancer - 1 Jun 2012

Zhou Ping, Liu Jian, Cheng Shao-Wen, Wang Bing, Yang Rong, Peng Ling

Abstract excerpt

Hereditary medullary thyroid carcinoma (hereditary MTC) is a rare malignancy, accounting for 25-30% of all MTC. It occurs as part of multiple endocrine neoplasia type 2 (MEN 2). Autosomal dominant gain-of-function mutations in the RET proto-oncogene is the cause of the disease, in which the common mutations are codons 609, 611, 618, 620, 630, 634 and 918. In recent years, the spectrum of RET gene mutations has...

Topics

Adult
Age Factors
Aged
Carcinoma, Medullary
Carcinoma, Neuroendocrine
Genetic Association Studies
Genetic Testing
Humans
Middle Aged
Mutation
Proto-Oncogene Mas
Proto-Oncogene Proteins c-ret
Thyroid Neoplasms
Thyroidectomy

Source

Open in PubMed

Identifiers

PMID: 22183190
DOI: 10.1007/s10689-011-9501-7

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics