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Article

Delineation of multiple deleted regions in 7q in myeloid disorders

1 Aug 1999

Abstract excerpt

Loss of chromosome material due to deletions of the long arm of chromosome 7, del(7q), is a consistent finding in all types of myeloid disorders, invariably associated with a poor prognosis. Two different segments, 7q22 and 7q32-q33, have been implicated as critical regions of gene loss associated with these disorders. In the present study, we used fluorescence in situ hybridization (FISH) to characterize the...

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PMID: 10398433
DOI: 10.1002/(sici)1098-2264(199908)25:4<384::aid-gcc11>3.0.co;2-d

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