Article
Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development.
Molecular cell - 1 Jul 2000
Adams R H, Porras A, Alonso G, Jones M, Vintersten K, Panelli S, Valladares A, Perez L, Klein R, Nebreda A R
Abstract excerpt
p38alpha MAP kinase is activated in response to many cellular stresses and also regulates the differentiation and/or survival of various cell types in vitro, including skeletal muscle cells and cardiomyocytes. Here we show that targeted inactivation of the mouse p38alpha gene results in embryonic...
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