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Article

JunB is essential for mammalian placentation.

The EMBO journal - 15 Feb 1999

Schorpp-Kistner M, Wang Z Q, Angel P, Wagner E F

Abstract excerpt

Lack of JunB, an immediate early gene product and member of the AP-1 transcription factor family causes embryonic lethality between E8.5 and E10.0. Although mutant embryos are severely retarded in growth and development, cellular proliferation is apparently not impaired. Retardation and embryonic death are caused by the inability of JunB-deficient embryos to establish proper vascular interactions with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10022836
DOI: 10.1093/emboj/18.4.934
PMCID: PMC1171186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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JunB is essential for mammalian placentation.PMID 10022836Read ↗

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Junb controls lymphatic vascular development in zebrafish via miR-182.Semantic proximity Read ↗

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects.Semantic proximity Read ↗

AP-1 Subunit JUNB Promotes Invasive Phenotypes in Endometriosis.Semantic proximity Read ↗

Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development.Semantic proximity Read ↗

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