Article
Homologous tails? Or tales of homology?
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Sept 2000
McGhee J D
Abstract excerpt
Classical mutations at the mouse Brachyury (T) locus were discovered because they lead to shortened tails in heterozygous newborns. no tail (ntl) mutants in the zebrafish, as their name suggests, show a similar phenotype. In Drosophila, mutants in the brachyenteron (byn) gene disrupt hindgut formation. These genes all encode T-box proteins, a class of sequence-specific DNA binding proteins and transcription...
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