Article
Sex-specific modifiers of tail development in mice heterozygous for the brachyury (T) mutation.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 1998
Agulnik I I, Agulnik S I, Saatkamp B D, Silver L M
Abstract excerpt
The brachyury, or T, locus encodes a transcription factor that plays a crucial role in the early development of all animals. In the mouse, animals heterozygous for a null mutation at this locus are born with a characteristic short tail. Expressivity of the short tail phenotype is greatly affected...
Topics
- Animals
- DNA-Binding Proteins
- Female
- Fetal Proteins
- Gene Expression Regulation, Developmental
- Genetic Linkage
- Genetic Markers
- Genotype
- Heterozygote
- Male
- Mice
- Microsatellite Repeats
