Article
Early evolution of the T-box transcription factor family.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2013
Sebé-Pedrós Arnau, Ariza-Cosano Ana, Weirauch Matthew T, Leininger Sven, Yang Ally, Torruella Guifré, Adamski Marcin, Adamska Maja, Hughes Timothy R, Gómez-Skarmeta José Luis, Ruiz-Trillo Iñaki
Abstract excerpt
Developmental transcription factors are key players in animal multicellularity, being members of the T-box family that are among the most important. Until recently, T-box transcription factors were thought to be exclusively present in metazoans. Here, we report the presence of T-box genes in several nonmetazoan lineages, including ichthyosporeans, filastereans, and fungi. Our data confirm that Brachyury is the...
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