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Article

Mutation detection by pyrosequencing: sequencing of exons 5-8 of the p53 tumor suppressor gene.

Gene - 8 Aug 2000

Garcia C A, Ahmadian A, Gharizadeh B, Lundeberg J, Ronaghi M, Nyrén P

Abstract excerpt

The ability to sequence a large number of DNA samples rapidly and accurately for detection of all possible mutations is a critical goal for the future application of DNA sequencing in routine medical diagnostics. Pyrosequencing() is a non-electrophoretic real-time DNA sequencing method that uses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10940563
DOI: 10.1016/s0378-1119(00)00257-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10940563-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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