Article
Mismatch repair protein MutL becomes limiting during stationary-phase mutation.
Genes & development - 15 Sept 1997
Harris R S, Feng G, Ross K J, Sidhu R, Thulin C, Longerich S, Szigety S K, Winkler M E, Rosenberg S M
Abstract excerpt
Postsynthesis mismatch repair is an important contributor to mutation avoidance and genomic stability in bacteria, yeast, and humans. Regulation of its activity would allow organisms to regulate their ability to evolve. That mismatch repair might be down-regulated in stationary-phase Escherichia coli was suggested by the sequence spectrum of some stationary-phase ("adaptive") mutations and by the observations...
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