Article
Association of lipoprotein lipase Ser447Ter polymorphism with brain infarction: a population-based neuropathological study.
Annals of medicine - 1 Oct 2001
Myllykangas L, Polvikoski T, Sulkava R, Notkola I L, Rastas S, Verkkoniemi A, Tienari P J, Niinistö L, Hardy J, Pérez-Tur J, Kontula K, Haltia M
Abstract excerpt
BACKGROUND: Variants of the lipoprotein lipase (LPL) gene have been shown to influence serum lipid levels, risk of coronary heart disease and, as found recently, risk of clinical ischaemic cerebrovascular disease. Here we tested for an association between brain infarction and two common polymorphisms of the LPL gene, Ser447Ter and Asn291 Ser. METHOD: To avoid ascertainment and selection bias involved in many...
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