Article
Lipoprotein lipase genetic variation and gender-specific ischemic cerebrovascular disease risk.
Nutrition reviews - 1 Oct 2000
Ordovas J M
Abstract excerpt
The lipoprotein lipase gene is highly polymorphic, and several common mutations have been associated with an increased atherogenic lipid profile. One of these, Asn291Ser, was also found to be associated with increased ischemic heart disease in women. More recently, this same mutation, present in approximately 5% of the population, was also associated with increased ischemic cerebrovascular disease risk. The...
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