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Article

Distinct phenotypes of mutant mice lacking agrin, MuSK, or rapsyn.

Brain research. Developmental brain research - 14 May 1999

Gautam M, DeChiara T M, Glass D J, Yancopoulos G D, Sanes J R

Abstract excerpt

Differentiation of the postsynaptic membrane at the neuromuscular junction requires agrin, a nerve-derived signal; MuSK, a critical component of the agrin receptor in muscle; and rapsyn, a protein that interacts with acetylcholine receptors (AChRs). We showed previously that nerve-induced AChR aggregation is dramatically impaired in knockout mice lacking agrin, MuSK, or rapsyn. However, the phenotypes of these...

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Identifiers

PMID: 10320756
DOI: 10.1016/s0165-3806(99)00013-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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