Article
Targeting of recombinant agrin to axonal growth cones.
Molecular and cellular neurosciences - 1 Dec 2003
Neuhuber Birgit, Daniels Mathew P
Abstract excerpt
Targeting of proteins to specific subcellular locations within pre- and postsynaptic neurons is essential for synapse formation. The heparan sulfate proteoglycan agrin orchestrates postsynaptic differentiation of the neuromuscular junction and may be involved in synaptic development and signaling in the central nervous system (CNS). Agrin is expressed as transmembrane and secretory isoforms with distinct...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
