Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism.

Clinical chemistry - 1 Aug 2000

Hustad S, Ueland P M, Vollset S E, Zhang Y, Bjørke-Monsen A L, Schneede J

Abstract excerpt

BACKGROUND: Plasma total homocysteine (tHcy) is a risk factor for cardiovascular disease. tHcy concentrations are partly determined by folate, cobalamin, and vitamin B(6) status, and methylenetetrahydrofolate reductase (MTHFR) and other flavoenzymes are important for the biotransformation of these vitamins. This motivates the investigation of the possible relationship between riboflavin status and tHcy. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross-Sectional Studies
Share to Electrophoresis, Capillary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Folic Acid

Share to Homocysteine

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Oxidoreductases Acting on CH-NH Group Donors

Share to Regression Analysis

Share to Riboflavin

Source

Identifiers

PMID: 10926884

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphism.PMID 10926884Read ↗

Effect of riboflavin status on the homocysteine-lowering effect of folate in relation to the MTHFR (C677T) genotype.Semantic proximity Read ↗

The relationship between riboflavin and plasma total homocysteine in the Framingham Offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene.Semantic proximity Read ↗

Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.Semantic proximity Read ↗

Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphism.Semantic proximity Read ↗

The maternal homocysteine pathway is influenced by riboflavin intake and MTHFR polymorphisms without affecting the risk of orofacial clefts in the offspring.Semantic proximity Read ↗

Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status: implications for riboflavin requirements.Semantic proximity Read ↗

B-vitamins, homocysteine metabolism and CVD.Semantic proximity Read ↗

Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype.Semantic proximity Read ↗

Homocysteine, B-vitamins and CVD.Semantic proximity Read ↗

Phenotypic expression of the methylenetetrahydrofolate reductase 677C-->T polymorphism and flavin cofactor availability in thyroid dysfunction.Semantic proximity Read ↗

Riboflavin status, MTHFR genotype and blood pressure: current evidence and implications for personalised nutrition.Semantic proximity Read ↗

B-vitamins, methylenetetrahydrofolate reductase (MTHFR) and hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.