Article
Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.
The American journal of the medical sciences - 1 Feb 2006
Chuang Cherng Zee, Boyles Adrienne, Legardeur Barbara, Su Joseph, Japa Shanker, Lopez-S Alfredo
Abstract excerpt
BACKGROUND: Observational studies have shown an inverse relationship between vitamin B2 status and total homocysteine levels, a risk factor for cardiovascular disease. We hypothesize that intervention with riboflavin will lower total homocysteine levels. The total homocysteine lowering by the three genotypes (CC, CT, TT) of methylenetetrahydrofolate reductase polymorphism (677C-->T) was also studied. METHODS: The...
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